Mitigating sepsis with a CHARTSaaS RA-compliant IT solution

“Increased awareness, early presentation to a health care facility or early recognition of health care–associated sepsis, rapid administration of appropriate antibiotics, and urgent treatment according to locally developed guidelines can significantly reduce deaths from sepsis. Since such measures have reduced case fatality rates in high-income countries, however, the substantial burden carried by survivors of sepsis has become clearer. The sequelae of sepsis can include clinically significant physical, cognitive, and psychological disability that often goes unrecognized and untreated. In LMICs [low- and middle-income countries], postdischarge mortality after sepsis is about the same as sepsis-related mortality in the hospital, and perinatal sepsis poses great and ongoing risks for both mother and infant. Yet around the world, coordinated services for sepsis survivors are virtually nonexistent.”

The foregoing quotation from the article by Konrad Reinhart, MD, et al entitled “Recognizing Sepsis as a Global Health Priority — A WHO Resolution” published in the August 3, 2017, issue of The New England Journal of Medicine ( highlights timely detection and clinical intervention as essentials for complete and uncomplicated recovery. Most of what is described is achievable with cloud-based software and little or no impact on provider resources and facilities using an information technology (IT) solution compliant with The Cloud Healthcare Appliance Real-Time Solution as a Service (CHARTSaaS) reference architecture (RA).

A CHARTSaaS RA-compliant  IT solution provides an integrated development environment in the cloud, available by subscription, that healthcare provider subject matter experts can use to create IT applications a.k.a. “apps” for cognitive support, with little or no expert help from IT staff. Such apps can operate as systems of engagement with  professional providers and their patients to leverage on-premise legacy electronic health record and hospital information systems (EHRs/HISs) using secure and intelligent interoperability to automate such problematic and error-prone use cases as differential diagnosis and treatment planning. Furthermore, such apps are easily modifiable and should be to meet The Joint Commission Standards for continuous process improvement and optimization.

Please validate this CHARTSaaS RA proposition to your own satisfaction by reading the white paper at, viewing the tutorials posted on YouTube ( and and also by reviewing the details of CHARTSaaS™ and the CHARTSaaS RA™ in these presentations:

Healthcare providers will benefit significantly from appreciating and then applying a CHARTSaaS RA-compliant IT solution. To do so will mitigate medical mistakes (currently the third leading cause of patient deaths. per Makaray and Daniel (; thereby minimizing patient adverse events and optimizing clinical case outcomes while maximizing the cost-effectiveness of care and treatment, and also accelerating the accrual and facilitating the application of medical knowledge.

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